问题：想知道1-溴-3，4，5，-三氟苯的毒性
类型：求助 (悬赏分:3分)
提问：乐在其中
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版块：氟化学(maurice,)
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时间：2006-02-20 08:19:14 编辑加入/取消收藏订制/取消短消息举报该贴

他的CAS号为138526-69-9，还有它的危险性。

[该帖子已被乐在其中在2006-2-20 8:19:45编辑过]

回复人：j52558026,▲▲▲ () 时间：2006-02-20 10:02:50 编辑	1楼
从www.chemexper.com上查它的MSDS

回复人：乙酸乙酯,▲▲▲▲ (精细有机中间体) 时间：2006-02-20 10:03:02 编辑

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Material Safety Data Sheet

1-Bromo-3,4,5-trifluorobenzene, 99%

ACC# 98319 Section 1 - Chemical Product and Company Identification

MSDS Name: 1-Bromo-3,4,5-trifluorobenzene, 99%
Catalog Numbers: AC308370000, AC308370010, AC308370050
Synonyms: 3,4,5-Trifluorobromobenzene.
Company Identification:
Acros Organics N.V.
One Reagent Lane
Fair Lawn, NJ 07410
For information in North America, call: 800-ACROS-01
For emergencies in the US, call CHEMTREC: 800-424-9300

Section 2 - Composition, Information on Ingredients

CAS# Chemical Name Percent EINECS/ELINCS
138526-69-9 1-Bromo-3,4,5-trifluorobenzene 99 418-480-9

Section 3 - Hazards Identification

EMERGENCY OVERVIEW
Appearance: clear colorless to slightly yellow clear liquid. Flash Point: 44 deg C.
Warning! Causes respiratory tract irritation. Flammable liquid and vapor. Causes eye and skin irritation. May cause central nervous system depression. Dangerous for the environment.
Target Organs: Central nervous system, eyes, skin, mucous membranes.

Potential Health Effects
Eye: Causes eye irritation. May cause chemical conjunctivitis and corneal damage.
Skin: Causes skin irritation. May cause cyanosis of the extremities.
Ingestion: May cause gastrointestinal irritation with nausea, vomiting and diarrhea. The toxicological properties of this substance have not been fully investigated. Ingestion of large amounts may cause CNS depression.
Inhalation: Causes respiratory tract irritation. Aspiration may lead to pulmonary edema. Vapors may cause dizziness or suffocation. Can produce delayed pulmonary edema. May cause burning sensation in the chest.
Chronic: Effects may be delayed.

Section 4 - First Aid Measures

Eyes: Immediately flush eyes with plenty of water for at least 15 minutes, occasionally lifting the upper and lower eyelids. Get medical aid.
Skin: Get medical aid. Flush skin with plenty of water for at least 15 minutes while removing contaminated clothing and shoes. Wash clothing before reuse.
Ingestion: Never give anything by mouth to an unconscious person. Get medical aid. Do NOT induce vomiting. If conscious and alert, rinse mouth and drink 2-4 cupfuls of milk or water. Wash mouth out with water.
Inhalation: Remove from exposure and move to fresh air immediately. If not breathing, give artificial respiration. If breathing is difficult, give oxygen. Get medical aid. Do NOT use mouth-to-mouth resuscitation.
Notes to Physician: Treat symptomatically and supportively.

Section 5 - Fire Fighting Measures

General Information: As in any fire, wear a self-contained breathing apparatus in pressure-demand, MSHA/NIOSH (approved or equivalent), and full protective gear. Vapors may form an explosive mixture with air. Vapors can travel to a source of ignition and flash back. During a fire, irritating and highly toxic gases may be generated by thermal decomposition or combustion. Will burn if involved in a fire. Use water spray to keep fire-exposed containers cool. Containers may explode in the heat of a fire. Flammable liquid and vapor. Vapors may be heavier than air. They can spread along the ground and collect in low or confined areas. Runoff from fire control or dilution water may cause pollution.
Extinguishing Media: For small fires, use dry chemical, carbon dioxide, water spray or alcohol-resistant foam. For large fires, use water spray, fog, or alcohol-resistant foam. Use water spray to cool fire-exposed containers. Water may be ineffective. Do NOT use straight streams of water.
Flash Point: 44 deg C ( 111.20 deg F)
Autoignition Temperature: Not available.
Explosion Limits, Lower:Not available.
Upper: Not available.
NFPA Rating: (estimated) Health: 2; Flammability: 2; Instability: 0

Section 6 - Accidental Release Measures

General Information: Use proper personal protective equipment as indicated in Section 8.
Spills/Leaks: Absorb spill with inert material (e.g. vermiculite, sand or earth), then place in suitable container. Avoid runoff into storm sewers and ditches which lead to waterways. Clean up spills immediately, observing precautions in the Protective Equipment section. Remove all sources of ignition. Use a spark-proof tool. Provide ventilation. A vapor suppressing foam may be used to reduce vapors.

Section 7 - Handling and Storage

Handling: Ground and bond containers when transferring material. Use spark-proof tools and explosion proof equipment. Avoid breathing dust, vapor, mist, or gas. Avoid contact with eyes, skin, and clothing. Empty containers retain product residue, (liquid and/or vapor), and can be dangerous. Keep container tightly closed. Keep away from heat, sparks and flame. Avoid ingestion and inhalation. Use with adequate ventilation. Wash clothing before reuse. Do not pressurize, cut, weld, braze, solder, drill, grind, or expose empty containers to heat, sparks or open flames.
Storage: Keep away from sources of ignition. Store in a tightly closed container. Store in a cool, dry, well-ventilated area away from incompatible substances. Flammables-area.

Section 8 - Exposure Controls, Personal Protection

Engineering Controls: Facilities storing or utilizing this material should be equipped with an eyewash facility and a safety shower. Use adequate general or local explosion-proof ventilation to keep airborne levels to acceptable levels.
Exposure Limits Chemical Name ACGIH NIOSH OSHA - Final PELs
1-Bromo-3,4,5-trifluorobenzene none listed none listed none listed

OSHA Vacated PELs: 1-Bromo-3,4,5-trifluorobenzene: No OSHA Vacated PELs are listed for this chemical.
Personal Protective Equipment
Eyes: Wear chemical splash goggles.
Skin: Wear appropriate protective gloves to prevent skin exposure.
Clothing: Wear appropriate protective clothing to prevent skin exposure.
Respirators: Follow the OSHA respirator regulations found in 29 CFR 1910.134 or European Standard EN 149. Use a NIOSH/MSHA or European Standard EN 149 approved respirator if exposure limits are exceeded or if irritation or other symptoms are experienced.

Section 9 - Physical and Chemical Properties

Physical State: Clear liquid
Appearance: clear colorless to slightly yellow
Odor: Not available.
pH: Not available.
Vapor Pressure: Not available.
Vapor Density: 7.3
Evaporation Rate:Not available.
Viscosity: Not available.
Boiling Point: 47 - 49 deg C @ 60mmHg
Freezing/Melting Point:Not available.
Decomposition Temperature:Not available.
Solubility: Insoluble.
Specific Gravity/Density:1.76 g/cm3
Molecular Formula:BrC6H2F3
Molecular Weight:210.99

Section 10 - Stability and Reactivity

Chemical Stability: Stable at room temperature in closed containers under normal storage and handling conditions.
Conditions to Avoid: Ignition sources, excess heat.
Incompatibilities with Other Materials: Strong oxidizing agents.
Hazardous Decomposition Products: Carbon monoxide, carbon dioxide, hydrogen fluoride gas, hydrogen bromide.
Hazardous Polymerization: Has not been reported

Section 11 - Toxicological Information

RTECS#:
CAS# 138526-69-9 unlisted.
LD50/LC50:
Not available.

Carcinogenicity:
CAS# 138526-69-9: Not listed by ACGIH, IARC, NTP, or CA Prop 65.

Epidemiology: No information found
Teratogenicity: No information found
Reproductive Effects: No information found
Mutagenicity: No information found
Neurotoxicity: No information found
Other Studies:

Section 12 - Ecological Information

No information available.

Section 13 - Disposal Considerations

Chemical waste generators must determine whether a discarded chemical is classified as a hazardous waste. US EPA guidelines for the classification determination are listed in 40 CFR Parts 261.3. Additionally, waste generators must consult state and local hazardous waste regulations to ensure complete and accurate classification.
RCRA P-Series: None listed.
RCRA U-Series: None listed.

Section 14 - Transport Information

US DOT Canada TDG
Shipping Name: DOT regulated - small quantity provisions apply (see 49CFR173.4) No information available.
Hazard Class:
UN Number:
Packing Group:

Section 15 - Regulatory Information

US FEDERAL

TSCA
CAS# 138526-69-9 is not listed on the TSCA inventory. It is for research and development use only.
Health & Safety Reporting List
None of the chemicals are on the Health & Safety Reporting List.
Chemical Test Rules
None of the chemicals in this product are under a Chemical Test Rule.
Section 12b
None of the chemicals are listed under TSCA Section 12b.
TSCA Significant New Use Rule
None of the chemicals in this material have a SNUR under TSCA.
CERCLA Hazardous Substances and corresponding RQs
None of the chemicals in this material have an RQ.
SARA Section 302 Extremely Hazardous Substances
None of the chemicals in this product have a TPQ.
Section 313 No chemicals are reportable under Section 313.
Clean Air Act:
This material does not contain any hazardous air pollutants.
This material does not contain any Class 1 Ozone depletors.
This material does not contain any Class 2 Ozone depletors.
Clean Water Act:
None of the chemicals in this product are listed as Hazardous Substances under the CWA.
None of the chemicals in this product are listed as Priority Pollutants under the CWA.
None of the chemicals in this product are listed as Toxic Pollutants under the CWA.
OSHA:
None of the chemicals in this product are considered highly hazardous by OSHA.
STATE
CAS# 138526-69-9 is not present on state lists from CA, PA, MN, MA, FL, or NJ.

California Prop 65

California No Significant Risk Level: None of the chemicals in this product are listed.

European/International Regulations
European Labeling in Accordance with EC Directives
Hazard Symbols:
XN N
Risk Phrases:
R 10 Flammable.
R 38 Irritating to skin.
R 40 Limited evidence of a carcinogenic effect.
R 41 Risk of serious damage to eyes.
R 51/53 Toxic to aquatic organisms, may cause long-term adverse
effects in the aquatic environment.

Safety Phrases:
S 23 Do not inhale gas/fumes/vapour/spray.
S 26 In case of contact with eyes, rinse immediately with plenty of
water and seek medical advice.
S 36/37/39 Wear suitable protective clothing, gloves and eye/face pr
otection.
S 61 Avoid release to the environment. Refer to special instructions
/safety data sheets.

WGK (Water Danger/Protection)
CAS# 138526-69-9: No information available.
Canada - DSL/NDSL
None of the chemicals in this product are listed on the DSL or NDSL list.
Canada - WHMIS
This product has a WHMIS classification of D2B, B3.
This product has been classified in accordance with the hazard criteria of the Controlled Products Regulations and the MSDS contains all of the information required by those regulations.
Canadian Ingredient Disclosure List

Section 16 - Additional Information

MSDS Creation Date: 1/04/2001
Revision #4 Date: 10/03/2005

The information above is believed to be accurate and represents the best information currently available to us. However, we make no warranty of merchantability or any other warranty, express or implied, with respect to such information, and we assume no liability resulting from its use. Users should make their own investigations to determine the suitability of the information for their particular purposes. In no event shall Fisher be liable for any claims, losses, or damages of any third party or for lost profits or any special, indirect, incidental, consequential or exemplary damages, howsoever arising, even if Fisher has been advised of the possibility of such damages.

回复人：乙酸乙酯,▲▲▲▲ (精细有机中间体) 时间：2006-02-20 10:04:00 编辑	3楼
https://fscimage.fishersci.com/msds/98319.htm

回复人：乐在其中,▲▲▲▲ (这世界上最美好的东西有三个：纯净的自然、疲惫的微笑、深刻的方程) 时间：2006-02-20 10:05:09 编辑	4楼
已经打分了。

得分人：j52558026-3,乙酸乙酯-3,

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