问题：二乙醇胺的溴代反应
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提问：快乐的求知者
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版块：有机化学问题(jimuwei,fpcwin1211,netpanda,yjgzfl,Ftian,)
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时间：2006-02-23 16:54:15 编辑加入/取消收藏订制/取消短消息举报该贴

二乙醇胺的溴代，即把俩羟基用溴替代，如何操作？产物如何提纯？请各位朋友指教！非常感谢！

[该帖子被admin在2006-3-7 11:59:21转移至此]

回复人：ecustlian,▲▲▲ (相互学习,共同提高) 时间：2006-02-23 18:57:16 编辑

1楼

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Beilstein Data: Copyright (c) 1988-2005, Beilstein Institut zur Foerderung der Chemischen Wissenschaften licensed to Beilstein GmbH and MDL Information Systems GmbH. All rights reserved.
Reaction (Beilstein(2005/03):Reactions:Q01 hit 10, RX.ID 8699216)
Reaction ID 8699216
Reactant BRN 605315 2,2'-azanediyl-bis-ethanol
Product BRN 3613681 bis-(2-bromo-ethyl)-amine; hydrobromide
No. of Reaction Details 1
Find similar reactions click here

Field Availability List (Beilstein(2005/03):Reactions:Q01 hit 10, RX.ID 8699216)
Code Field Name Occ.
RX Reaction Details 1

Reaction Details (Beilstein(2005/03):Reactions:Q01 hit 10, RX.ID 8699216)
Reaction Classification Preparation
Reagent aq. HBr
Temperature 100 - 125 C
Reaction Type Bromination
Ref. 1 6267583; Journal; Flader, Carolee; Liu, Jiwen; Borch, Richard F.; JMCMAR; J. Med. Chem.; EN; 43; 16; 2000; 3157 - 3167.

RX.ID=8699216:

回复人：ecustlian,▲▲▲ (相互学习,共同提高) 时间：2006-02-23 18:58:54 编辑

2楼

Beilstein Data: Copyright (c) 1988-2005, Beilstein Institut zur Foerderung der Chemischen Wissenschaften licensed to Beilstein GmbH and MDL Information Systems GmbH. All rights reserved.
Reaction (Beilstein(2005/03):Reactions:Q01 hit 7, RX.ID 6950636)
Reaction ID 6950636
Reactant 2.2'-dihydroxy-diethylamine hydrobromide
Product BRN 1733830 bis-(2-bromo-ethyl)-amine
No. of Reaction Details 3
Find similar reactions not available

Field Availability List (Beilstein(2005/03):Reactions:Q01 hit 7, RX.ID 6950636)
Code Field Name Occ.
RX Reaction Details 3

Reaction Details 1 of 3 (Beilstein(2005/03):Reactions:Q01 hit 7, RX.ID 6950636)
Reaction Classification Preparation (half reaction)
Reagent HBr
Temperature 170 - 175 C
Note 1 Handbook
Ref. 1 1233465; Patent; I.G.Farbenind.; CH 188621; 1936; FTFVA6; Fortschr. Teerfarbenfabr. Verw. Industriezweige; DE; GE; 25; 79.
Ref. 2 1233466; Patent; I.G.Farbenind.; US 2136171; 1936.
Ref. 3 1233467; Patent; I.G.Farbenind.; FR 800369; 1936.

Reaction Details 2 of 3 (Beilstein(2005/03):Reactions:Q01 hit 7, RX.ID 6950636)
Reaction Classification Preparation (half reaction)
Reagent water

HBr
Temperature 100 - 200 C
Note 1 Handbook
Ref. 1 1233307; Journal; Prelog; Driza; Hanousek; CCCCAK; Collect. Czech. Chem. Commun.; 3; 1931; 579.

Reaction Details 3 of 3 (Beilstein(2005/03):Reactions:Q01 hit 7, RX.ID 6950636)
Reaction Classification Preparation (half reaction)
Reagent water

HBr
Temperature 120 - 130 C
Note 1 Handbook
Ref. 1 1233489; Journal; Peacock; Dutta; JCSOA9; J. Chem. Soc.; 1934; 1305.

RX.ID=6950636:

回复人：ecustlian,▲▲▲ (相互学习,共同提高) 时间：2006-02-23 19:00:08 编辑

3楼

回复人：ecustlian,▲▲▲ (相互学习,共同提高) 时间：2006-02-23 19:00:37 编辑	4楼
看看这些能对你有帮助吗

回复人：快乐的求知者,▲ (有点痴痴的求知欲) 时间：2006-03-07 08:53:22 编辑	5楼
已经打分了。

得分人：ecustlian-3,

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