问题：跪求2-氨基丙醇(L-氨基丙醇)合成方法
类型：求助 (悬赏分:3分)
提问：petroboy
等级：▲
版块：有机化学问题(jimuwei,fpcwin1211,netpanda,yjgzfl,Ftian,)
信誉：56%
回复：10
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时间：2006-03-01 10:03:07 编辑加入/取消收藏订制/取消短消息举报该贴

跪求2-氨基丙醇(L-氨基丙醇)工业合成方法,谢谢!

回复人：chemg,▲ () 时间：2006-03-01 11:42:27 编辑	1楼
从L-氨基丙酸或酯还原合成,具体文献到万方数据库查询.

回复人：maurice,★★ (自信,乐观,富于激情,积极面对人生) 时间：2006-03-01 14:01:45 编辑	2楼
Ｌ－２－氨基丙酸为原料，与氯化亚砜和无水乙醇反应成酯，再经硼氢化锌还原后，用液碱处理得Ｌ－２－氨基丙醇。二步合成总收率达６０％以上。其中硼氢化锌由硼氢化钾和无水氯化锌反应制得。　 [该帖子已被maurice在2006-3-3 14:58:53编辑过]

回复人：landlord,▲ (交流学术,共同进步) 时间：2006-03-01 21:22:57 编辑	3楼
"工业合成方法"!

回复人：petroboy,▲ (从事化工业务,虚心向大家请教问题.) 时间：2006-03-02 12:45:06 编辑	4楼
工业怎么合成的?

回复人：zangjb,★ (精细化工研究开发) 时间：2006-03-02 16:53:24 编辑	5楼
我发给你1份资料，你自己收一下你的邮箱吧。

回复人：ecustlian,▲▲▲ (相互学习,共同提高) 时间：2006-03-02 20:13:01 编辑

6楼

Reaction (Beilstein(2005/03):Reactions:Q01 hit 42, RX.ID 6395577)
Reaction ID 6395577
Product BRN 1209234 2-amino-propan-1-ol
No. of Reaction Details 1
Find similar reactions not available

Field Availability List (Beilstein(2005/03):Reactions:Q01 hit 42, RX.ID 6395577)
Code Field Name Occ.
RX Reaction Details 1

Reaction Details (Beilstein(2005/03):Reactions:Q01 hit 42, RX.ID 6395577)
Reaction Classification Preparation (half reaction)
Ref. 1 3997226; Journal; Ingram; Wood; JBCHA3; J. Biol. Chem.; 240; 1965; 4146.
Ref. 2 4076089; Journal; Yamaguchi; Yoshioka; NKAKB8; Nippon Kagaku Kaishi; 1979; 517,518,519; Chem.Abstr.; 91; 90831; 1979.
Ref. 3 3118128; Patent; Kyowa Hakko Kogyo; DE 2810923; 1978; Chem.Abstr.; EN; 90; 38929.
Ref. 4 4218446; Patent; Rikagahn Konkjuse; JP 4823554; 1978; RZKHAR; Ref. Zh. Khim.; RU; 15; N185P; 1979.
Ref. 5 4496909; Journal; Samyn et al.; MACEAK; Makromol. Chem.; 177; 1976; 2849,2858.
Ref. 6 4511710; Patent; Jefferson Chemical Co.; US 3448153; 1966; Chem.Abstr.; EN; 71; 49235k; 1969.
Ref. 7 4532716; Journal; Bunnett et al.; JACSAT; J. Am. Chem. Soc.; 96; 1974; 2855,2856, 2857.
Ref. 8 4097112; Journal; Torf; MPSSA9; Med. Promst. SSSR; 19; 1965; 26; Chem.Abstr.; 63; 11417g; 1965.
Ref. 9 215033; Journal; Yonemitsu,O. et al.; TELEAY; Tetrahedron Lett.; EN; 1968; 3575-3578.

RX.ID=6395577:

回复人：ecustlian,▲▲▲ (相互学习,共同提高) 时间：2006-03-02 20:13:36 编辑

7楼

Reaction ID 6932278
Reactant ergometrinine
Product BRN 1718865 (S)-2-amino-propan-1-ol
No. of Reaction Details 1
Find similar reactions not available

Field Availability List (Beilstein(2005/03):Reactions:Q01 hit 43, RX.ID 6932278)
Code Field Name Occ.
RX Reaction Details 1

Reaction Details (Beilstein(2005/03):Reactions:Q01 hit 43, RX.ID 6932278)
Reaction Classification Preparation (half reaction)
Reagent concentrated HCl
Note 1 Handbook
Ref. 1 664166; Journal; Smith; Timmis; JCSOA9; J. Chem. Soc.; 1936; 1166.

RX.ID=6932278:

--------------------------------------------------------------------------------
Beilstein Data: Copyright (c) 1988-2005, Beilstein Institut zur Foerderung der Chemischen Wissenschaften licensed to Beilstein GmbH and MDL Information Systems GmbH. All rights reserved.
Reaction (Beilstein(2005/03):Reactions:Q01 hit 44, RX.ID 6932279)
Reaction ID 6932279
Reactant ergometrine
Product BRN 1718865 (S)-2-amino-propan-1-ol
No. of Reaction Details 1
Find similar reactions not available

Field Availability List (Beilstein(2005/03):Reactions:Q01 hit 44, RX.ID 6932279)
Code Field Name Occ.
RX Reaction Details 1

Reaction Details (Beilstein(2005/03):Reactions:Q01 hit 44, RX.ID 6932279)
Reaction Classification Preparation (half reaction)
Reagent concentrated HCl
Note 1 Handbook
Ref. 1 1238876; Journal; Jacobs; Craig; SCIEAS; Science (Washington, D.C.,1883-); 82; 1935; 17; CHZEA6; Chem. Zentralbl.; GE; 106; II; 1935; 2821.
Ref. 2 664166; Journal; Smith; Timmis; JCSOA9; J. Chem. Soc.; 1936; 1166.

RX.ID=6932279:

回复人：ecustlian,▲▲▲ (相互学习,共同提高) 时间：2006-03-02 20:13:55 编辑

8楼

Beilstein Data: Copyright (c) 1988-2005, Beilstein Institut zur Foerderung der Chemischen Wissenschaften licensed to Beilstein GmbH and MDL Information Systems GmbH. All rights reserved.
Reaction (Beilstein(2005/03):Reactions:Q01 hit 46, RX.ID 6932281)
Reaction ID 6932281
Reactant N-benzyloxycarbonyl-D-thioalanine S-methyl ester
Product BRN 1718866 (R)-2-amino-propan-1-ol
No. of Reaction Details 1
Find similar reactions not available

Field Availability List (Beilstein(2005/03):Reactions:Q01 hit 46, RX.ID 6932281)
Code Field Name Occ.
RX Reaction Details 1

Reaction Details (Beilstein(2005/03):Reactions:Q01 hit 46, RX.ID 6932281)
Reaction Classification Preparation (half reaction)
Reagent Raney nickel

diethyl ether
Note 1 Handbook
Ref. 1 1562613; Journal; Jeger et al.; HCACAV; Helv. Chim. Acta; 29; 1946; 684, 688.

RX.ID=6932281:

回复人：petroboy,▲ (从事化工业务,虚心向大家请教问题.) 时间：2006-03-03 10:25:38 编辑	9楼
收了,谢谢大家的热心帮助.

回复人：petroboy,▲ (从事化工业务,虚心向大家请教问题.) 时间：2006-03-03 10:30:15 编辑	10楼
已经打分了。

得分人：maurice-2,

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