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问题：冰天雪地裸跪求间三氟甲基苯丙酮的合成文献
类型：求助 (悬赏分:3分)
提问：lwdsysy030
等级：▲
版块：氟化学(maurice,)
信誉：25%
回复：10
阅读：2624
时间：2006-03-02 09:24:34  编辑    加入/取消收藏    订制/取消短消息    举报该贴    

冰天雪地裸跪求间三氟甲基苯丙酮的合成文献，有用的给加分，谢谢先了！
回复人：maurice,★★ (自信,乐观,富于激情,积极面对人生) 时间：2006-03-03 08:59:37   编辑 1楼
兄弟还是站起来，把衣服穿上吧！


回复人：zhangquee,▲▲▲▲ (药物合成) 时间：2006-03-04 20:23:25   编辑 2楼
先站起来，在看看我给你的东西对你有没有用！！
1-[3-(Trifluoromethyl)phenyl]-2-propanone；1-(,,-Trifluoro-m-tolyl)-2-propanone； 3-(Trifluoromethyl)phenylacetone。CAS Registry Number: 21906-39-8：
相关合成文献：
Binovic, K. et al., Chim. Ther., 1968, 3, 313; CA, 70, 87171y, (synth)
Dehnel, A. et al., Synthesis, 1977, 474, (synth)
Durandetti, M. et al., Synth. Commun., 1994, 24, 145, (synth)
以后别用跪字了，没有必要这样的 ！！


回复人：tangyyer,★★★★★ (有空来逛逛my blog: http://tangyyer.blog.hexun.com) 时间：2006-03-04 21:19:49   编辑 3楼
参见文献Tetrahedron Letters (2004), 45(32), 6159-6163；Journal of Organic Chemistry (2001), 66(19), 6495-6497； Tetrahedron: Asymmetry (1998), 9(13), 2317-2327；Huaxue Yanjiu Yu Yingyong (1997), 9(2), 135-137；Journal of Organic Chemistry (1996), 61(5), 1748-55；Shenyang Yaoke Daxue Xuebao (1995), 12(3), 171-3；Shenyang Yaoxueyuan Xuebao (1994), 11(2), 116-18，应该够了，94年前的就不发了。


回复人：ecustlian,▲▲▲ (相互学习,共同提高) 时间：2006-03-05 21:57:34   编辑 4楼
Beilstein Data: Copyright (c) 1988-2005, Beilstein Institut zur Foerderung der Chemischen Wissenschaften licensed to Beilstein GmbH and MDL Information Systems GmbH. All rights reserved.
Field Availability List (Beilstein(2005/03):Reactions:Q01 hit 4, RX.ID 3346431)
Code Field Name Occ.
RX Reaction Details 2

Reaction Details 1 of 2 (Beilstein(2005/03):Reactions:Q01 hit 4, RX.ID 3346431)
Reaction Classification Preparation
Yield 79 percent (BRN=1454749)
Reagent Bu4NBF4, NiBr2bpy
Temperature 80 C
Other Conditions Al rod/nickel-sponge, electrolysis
Ref. 1 5896202; Journal; Durandetti, Muriel; Sibille, Soline; Nedelec, Jean-Yves; Perichon, Jacques; SYNCAV; Synth. Commun.; EN; 24; 2; 1994; 145-152.

Reaction Details 2 of 2 (Beilstein(2005/03):Reactions:Q01 hit 4, RX.ID 3346431)
Reaction Classification Preparation
Yield 80 percent (BRN=1454749)
Reagent NBu4BF4, NiBr2bipy
Solvent dimethylformamide
Temperature 70 C
Other Conditions i = 250 mA, nickel-sponge cathode
Ref. 1 6013386; Journal; Durandetti, Muriel; Nedelec, Jean-Yves; Perichon, Jacques; JOCEAH; J. Org. Chem.; EN; 61; 5; 1996; 1748-1755.

--------------------------------------------------------------------------------
Beilstein Data: Copyright (c) 1988-2005, Beilstein Institut zur Foerderung der Chemischen Wissenschaften licensed to Beilstein GmbH and MDL Information Systems GmbH. All rights reserved.
Reaction (Beilstein(2005/03):Reactions:Q01 hit 10, RX.ID 6592775)
Reaction ID 6592775
Product BRN 1454749 3-(trifluoromethyl)phenylacetone
No. of Reaction Details 1
Find similar reactions not available

Field Availability List (Beilstein(2005/03):Reactions:Q01 hit 10, RX.ID 6592775)
Code Field Name Occ.
RX Reaction Details 1

Reaction Details (Beilstein(2005/03):Reactions:Q01 hit 10, RX.ID 6592775)
Reaction Classification Preparation (half reaction)
Ref. 1 4181245; Patent; Synthelabo; FR 2289487; 1976; DE 2455914; Chem.Abstr.; EN; 83; 205903.
Ref. 2 5189756; Patent; Soc. Oril.; FR 1457540; 1966; Chem.Abstr.; EN; 67; 90535.

RX.ID=6592775:




回复人：ecustlian,▲▲▲ (相互学习,共同提高) 时间：2006-03-05 21:57:34   编辑 5楼
Beilstein Data: Copyright (c) 1988-2005, Beilstein Institut zur Foerderung der Chemischen Wissenschaften licensed to Beilstein GmbH and MDL Information Systems GmbH. All rights reserved.
Field Availability List (Beilstein(2005/03):Reactions:Q01 hit 4, RX.ID 3346431)
Code Field Name Occ.
RX Reaction Details 2

Reaction Details 1 of 2 (Beilstein(2005/03):Reactions:Q01 hit 4, RX.ID 3346431)
Reaction Classification Preparation
Yield 79 percent (BRN=1454749)
Reagent Bu4NBF4, NiBr2bpy
Temperature 80 C
Other Conditions Al rod/nickel-sponge, electrolysis
Ref. 1 5896202; Journal; Durandetti, Muriel; Sibille, Soline; Nedelec, Jean-Yves; Perichon, Jacques; SYNCAV; Synth. Commun.; EN; 24; 2; 1994; 145-152.

Reaction Details 2 of 2 (Beilstein(2005/03):Reactions:Q01 hit 4, RX.ID 3346431)
Reaction Classification Preparation
Yield 80 percent (BRN=1454749)
Reagent NBu4BF4, NiBr2bipy
Solvent dimethylformamide
Temperature 70 C
Other Conditions i = 250 mA, nickel-sponge cathode
Ref. 1 6013386; Journal; Durandetti, Muriel; Nedelec, Jean-Yves; Perichon, Jacques; JOCEAH; J. Org. Chem.; EN; 61; 5; 1996; 1748-1755.

--------------------------------------------------------------------------------
Beilstein Data: Copyright (c) 1988-2005, Beilstein Institut zur Foerderung der Chemischen Wissenschaften licensed to Beilstein GmbH and MDL Information Systems GmbH. All rights reserved.
Reaction (Beilstein(2005/03):Reactions:Q01 hit 10, RX.ID 6592775)
Reaction ID 6592775
Product BRN 1454749 3-(trifluoromethyl)phenylacetone
No. of Reaction Details 1
Find similar reactions not available

Field Availability List (Beilstein(2005/03):Reactions:Q01 hit 10, RX.ID 6592775)
Code Field Name Occ.
RX Reaction Details 1

Reaction Details (Beilstein(2005/03):Reactions:Q01 hit 10, RX.ID 6592775)
Reaction Classification Preparation (half reaction)
Ref. 1 4181245; Patent; Synthelabo; FR 2289487; 1976; DE 2455914; Chem.Abstr.; EN; 83; 205903.
Ref. 2 5189756; Patent; Soc. Oril.; FR 1457540; 1966; Chem.Abstr.; EN; 67; 90535.

RX.ID=6592775:




回复人：Ftian,★★ (资料请发到我的邮箱里，这里封纳米盘。) 时间：2006-03-06 22:17:19   编辑 6楼
1 Tetrahedron Letters (2004), 45(32), 6159-6163
2 Journal of Organic Chemistry (2001), 66(19), 6495-6497
3 Tetrahedron: Asymmetry (1998), 9(13), 2317-2327.
4 EP 810195
5 Huaxue Yanjiu Yu Yingyong (1997), 9(2), 135-137
6 New Journal of Chemistry (1996), 20(3), 375-83
7 Journal of Organic Chemistry (1996), 61(5), 1748-55
8 Shenyang Yaoke Daxue Xuebao (1995), 12(3), 171-3
9 Shenyang Yaoxueyuan Xuebao (1994), 11(2), 116-18
10 Synthetic Communications (1994), 24(2), 145-5
11 Bulletin de la Societe Chimique de France (1993), 130(4), 459-66
12 FR 2629474
13 Tetrahedron Letters (1986), 27(35), 4175-6
14 Gaodeng Xuexiao Huaxue Xuebao (1988), 9(2), 134-9
15 Synthesis (1977), (7), 474-6
16 Chemical & Pharmaceutical Bulletin (1975), 23(11), 2620-8
17 DE 2455914
18 Chimica Therapeutica (1968), 3(5), 313-20
够了吧?


回复人：lwdsysy030,▲ (一个化工事业的爱好者,来此请教各路高手,还请多多关照!) 时间：2006-03-07 08:51:13   编辑 7楼
谢谢大伙了，真的。（激动的泪水在眼眶里打转）


回复人：tiger2008,▲ (黄药师) 时间：2007-07-29 02:07:11   编辑 8楼
靠，有必要这样么？


回复人：zjr1980,▲ (从事合成四年，自感小有经验。) 时间：2007-08-02 10:18:26   编辑 9楼
兄弟真会说话


回复人：甲基,▲ (甲基苯丙胺) 时间：2007-08-23 21:57:18   编辑 10楼




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