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问题:Comprehensive Organic Functional Group Transformations II, V. 5
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时间:2006-07-27 13:40:37  编辑    加入/取消收藏    订制/取消短消息    举报该贴    

volume 5: Carbon with Two Attached Heteroatoms with at Least One Carbon-to-Heteroatom Multiple Link

In the decade since 1995, there has been a great deal of activity in the area covered by this volume. The rather cumbersome title of ‘‘Carbons with two attached heteroatoms with at least one carbon-to-heteroatom multiple link’’ encompasses a range of very important functionalities.
The most familiar, and one might mistakenly think, fully investigated carboxylate derivatives, such as carboxylic acids, acid halides, esters, and amides, have all seen advances. In the case of amides, this is particularly driven by the peptide synthesis arena, and natural product synthesis also remains a major motivation. Other acyl derivatives, including acyl metals, have seen major developments. Thionoamides and amidines remain important functional groups – the latter, of
course, for their potential in heterocycle synthesis amongst others. Metal carbenoids, isocyanates, and carbodiimides are just a few more examples where significant new methodology has appeared. Applications of solid-phase organic synthesis appear in a few chapters.
It is impossible to encapsulate in a short introduction, the many real advances in synthesis of the range of important functional groups covered by this volume – each reader will have favorites, depending on their area of chemical interest. Suffice to say, this volume has something for everyone interested in organic synthesis, since the functions reviewed are core to the synthetic arena.

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回复人:yjgzfl, (研究) 时间:2006-07-30 10:45:48   编辑 1楼
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