问题：请教一个化合物的合成
类型：求助 (悬赏分:3分)
提问：xjk751009
等级：▲▲
版块：有机化学问题(jimuwei,fpcwin1211,netpanda,yjgzfl,Ftian,)
信誉：62%
回复：5
阅读：684
时间：2006-09-06 14:24:44 编辑加入/取消收藏订制/取消短消息举报该贴

1-bromo-2-ethylbutane
cas：3814-34-4
请教各位同行上述化合物（1）如何合成？（2）国内有无生产厂家？（3）能否提供相关参考文献或有关信息？
先谢过了。

回复人：edwin,★★ (宝剑锋从磨砺出,梅花香自苦寒来) 时间：2006-09-06 14:46:22 编辑	1楼
参考: J.Am.Chem.Soc., 1936, 58, 585

回复人：xjk751009,▲▲ (一个喜欢有机合成的青年。) 时间：2006-09-07 11:03:53 编辑	2楼
多谢EDMIN，能否帮我下载该篇文献，先谢过了。

回复人：飘逸雪,★ (将天然有机产物的合成做为艺术的一个合成人) 时间：2006-09-07 22:20:13 编辑

3楼

已经给你了
Language: EN
Country:

**** MATERIAL SAFETY DATA SHEET ****

1-Bromo-2-ethylbutane, 97%

**** SECTION 1 - CHEMICAL PRODUCT AND COMPANY IDENTIFICATION ****

MSDS Name: 1-Bromo-2-ethylbutane, 97%
Catalog Numbers:
30518-0000, 30518-0050, 30518-0250
Synonyms:
3-(Bromomethyl)pentane
Company Identification (Europe): Acros Organics BVBA
Janssen Pharmaceuticalaan 3a
2440 Geel, Belgium
Company Identification (USA): Acros Organics
One Reagent Lane
Fairlawn, NJ 07410
For information in North America, call: 800-ACROS-01
For information in Europe, call: 0032(0) 14575211
For emergencies in the US, call CHEMTREC: 800-424-9300
For emergencies in Europe, call: 0032(0) 14575299

**** SECTION 2 - COMPOSITION, INFORMATION ON INGREDIENTS ****

+----------------+--------------------------------------+----------+-----------+-----------+---------------+
| CAS# | Chemical Name | % | EINECS# |Haz Symbols| Risk Phrases |
|----------------|--------------------------------------|----------|-----------|-----------|---------------+
| 3814-34-4 |1-Bromo-2-ethylbutane | 97% | 223-302-6 |||
+----------------+--------------------------------------+----------+-----------+-----------+---------------+
Hazard Symbols: XI
Risk Phrases: 10 36/37/38

**** SECTION 3 - HAZARDS IDENTIFICATION ****

EMERGENCY OVERVIEW
Flammable. Irritating to eyes, respiratory system and skin.

Potential Health Effects
Eye:
Causes eye irritation.
Skin:
Causes skin irritation. May be harmful if absorbed through the skin.
Ingestion:
May cause irritation of the digestive tract. May be harmful if
swallowed.
Inhalation:
Causes respiratory tract irritation. May be harmful if inhaled.
Chronic:
Not available.

**** SECTION 4 - FIRST AID MEASURES ****

Eyes:
Flush eyes with plenty of water for at least 15 minutes,
occasionally lifting the upper and lower eyelids. Get medical aid.
Skin:
Get medical aid. Flush skin with plenty of water for at least 15
minutes while removing contaminated clothing and shoes.
Ingestion:
Get medical aid. Wash mouth out with water.
Inhalation:
Remove from exposure and move to fresh air immediately. If not
breathing, give artificial respiration. If breathing is difficult,
give oxygen. Get medical aid.
Notes to Physician:
Treat symptomatically and supportively.

**** SECTION 5 - FIRE FIGHTING MEASURES ****

General Information:
As in any fire, wear a self-contained breathing apparatus in
pressure-demand, MSHA/NIOSH (approved or equivalent), and full
protective gear. Vapors may form an explosive mixture with air.
Vapors can travel to a source of ignition and flash back. Will burn
if involved in a fire. Containers may explode in the heat of a fire.
Flammable liquid and vapor.
Extinguishing Media:
Use water spray to cool fire-exposed containers. Use foam, dry
chemical, or carbon dioxide.

**** SECTION 6 - ACCIDENTAL RELEASE MEASURES ****

General Information: Use proper personal protective equipment as indicated
in Section 8.
Spills/Leaks:
Absorb spill with inert material (e.g. vermiculite, sand or earth),
then place in suitable container. Remove all sources of ignition.
Use a spark-proof tool.

**** SECTION 7 - HANDLING and STORAGE ****

Handling:
Use spark-proof tools and explosion proof equipment. Avoid breathing
dust, vapor, mist, or gas. Avoid contact with skin and eyes. Take
precautionary measures against static discharges. Use only in a
chemical fume hood.
Storage:
Keep away from sources of ignition. Store in a cool, dry place.
Store in a tightly closed container. Keep under a nitrogen blanket.
Flammables-area.

**** SECTION 8 - EXPOSURE CONTROLS, PERSONAL PROTECTION ****

Engineering Controls:
Facilities storing or utilizing this material should be equipped
with an eyewash facility and a safety shower. Use adequate general or
local explosion-proof ventilation to keep airborne levels to
acceptable levels.
Personal Protective Equipment

Eyes:
Wear chemical goggles.
Skin:
Wear appropriate protective gloves to prevent skin
exposure.
Clothing:
Wear appropriate protective clothing to prevent skin
exposure.
Respirators:
Follow the OSHA respirator regulations found in 29
CFR 1910.134 or European Standard EN 149. Always use
a NIOSH or European Standard EN 149 approved
respirator when necessary.

**** SECTION 9 - PHYSICAL AND CHEMICAL PROPERTIES ****

Physical State: Liquid
Color: light yellow
Odor: sweetish odor
pH: Not available.
Vapor Pressure: Not available.
Viscosity: Not available.
Boiling Point: 143 - 144 deg C @ 760mmHg
Freezing/Melting Point: Not available.
Autoignition Temperature: Not available.
Flash Point: 35 deg C ( 95.00 deg F)
Explosion Limits, lower: Not available.
Explosion Limits, upper: Not available.
Decomposition Temperature:
Solubility in water:
Specific Gravity/Density: 1.1790g/cm3
Molecular Formula: C6H13Br
Molecular Weight: 165.08

**** SECTION 10 - STABILITY AND REACTIVITY ****

Chemical Stability:
Stable.
Conditions to Avoid:
Incompatible materials, light, ignition sources.
Incompatibilities with Other Materials:
Strong oxidizing agents, strong bases.
Hazardous Decomposition Products:
Carbon monoxide, carbon dioxide, hydrogen bromide.
Hazardous Polymerization: Will not occur.

**** SECTION 11 - TOXICOLOGICAL INFORMATION ****

RTECS#:
CAS# 3814-34-4 unlisted.
LD50/LC50:
Not available.
Carcinogenicity:
1-Bromo-2-ethylbutane -
Not listed by ACGIH, IARC, NIOSH, NTP, or OSHA.
See actual entry in RTECS for complete information.

**** SECTION 12 - ECOLOGICAL INFORMATION ****

Other
Do not empty into drains.

**** SECTION 13 - DISPOSAL CONSIDERATIONS ****

Dispose of in a manner consistent with federal, state, and local regulations.

**** SECTION 14 - TRANSPORT INFORMATION ****

IATA
Shipping Name: FLAMMABLE LIQUID, N.O.S.*
Hazard Class: 3
UN Number: 1993
Packing Group: III
IMO
Shipping Name: FLAMMABLE LIQUID, N.O.S.
Hazard Class: 3
UN Number: 1993
Packing Group: III
RID/ADR
Shipping Name: FLAMMABLE LIQUID, N.O.S.
Hazard Class: 3
UN Number: 1993
Packing group: III

**** SECTION 15 - REGULATORY INFORMATION ****

European/International Regulations
European Labeling in Accordance with EC Directives
Hazard Symbols: XI
Risk Phrases:
R 10 Flammable.
R 36/37/38 Irritating to eyes, respiratory system
and skin.
Safety Phrases:
S 16 Keep away from sources of ignition - No
smoking.
S 26 In case of contact with eyes, rinse immediately
with plenty of water and seek medical advice.
S 37/39 Wear suitable gloves and eye/face
protection.
WGK (Water Danger/Protection)
CAS# 3814-34-4: No information available.
United Kingdom Occupational Exposure Limits

United Kingdom Maximum Exposure Limits

Canada
CAS# 3814-34-4 is listed on Canada's NDSL List.
CAS# 3814-34-4 is not listed on Canada's Ingredient Disclosure List.
Exposure Limits
US FEDERAL
TSCA
CAS# 3814-34-4 is listed on the TSCA inventory.

**** SECTION 16 - ADDITIONAL INFORMATION ****

MSDS Creation Date: 11/12/1996 Revision #1 Date: 2/01/2001

The information above is believed to be accurate and represents the best
information currently available to us. However, we make no warranty of
merchantability or any other warranty, express or implied, with respect to
such information, and we assume no liability resulting from its use. Users
should make their own investigations to determine the suitability of the
information for their particular purposes. In no way shall the company be
liable for any claims, losses, or damages of any third party or for lost
profits or any special, indirect, incidental, consequential or exemplary
damages, howsoever arising, even if the company has been advised of
the possibility of such damages.
-----------------------------------------------

回复人：飘逸雪,★ (将天然有机产物的合成做为艺术的一个合成人) 时间：2006-09-07 22:22:44 编辑

4楼

合成的文献在www.orgsyn.org你自己看一下了
性质在这里了
Physical State:　　　　　　 Liquid
Color:　　　　　　　　　　　light yellow
Odor:　　　　　　　　　　　 sweetish odor
pH:　　　　　　　　　　　　 Not available.
Vapor Pressure:　　　　　　 Not available.
Viscosity:　　　　　　　　　Not available.
Boiling Point:　　　　　　　143 - 144 deg C @ 760mmHg
Freezing/Melting Point:　　 Not available.
Autoignition Temperature:　 Not available.
Flash Point:　　　　　　　　35 deg C ( 95.00 deg F)
Explosion Limits, lower:　　Not available.
Explosion Limits, upper:　　Not available.
Decomposition Temperature:
Solubility in water:
Specific Gravity/Density:　 1.1790g/cm3
Molecular Formula:　　　　　C6H13Br
Molecular Weight:　　　　　 165.08

回复人：xjk751009,▲▲ (一个喜欢有机合成的青年。) 时间：2006-09-08 09:49:41 编辑	5楼
谢谢

得分人：edwin-3,飘逸雪-2,

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