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回复人:claymore,★★★★★ (C-H活化,kumada,suzuki,stille,negishi.cross-coupling.) 时间:2009-12-29 23:51:25   编辑 1楼
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回复人:claymore,★★★★★ (C-H活化,kumada,suzuki,stille,negishi.cross-coupling.) 时间:2009-12-29 23:53:49   编辑 2楼
Author: A.S. Grandison

Product Details
* Hardcover: 302 pages
* Publisher: CRC; 1 edition (July 10, 1996)
* Language: English
* ISBN-10: 1566764904
* ISBN-13: 978-1566764902
* Product Dimensions: 9.9 x 6.7 x 0.9 inches

Product Description
From the Editors' Preface

This book concentrates on the more recent methods and techniques for separating food components and products of the biotechnology industry. Each chapter deals with a specific type or area of application and includes information on the basic principles, industrial equipment available, commercial applications, and an overview of current research and development.
Much of the emphasis is on extraction of macromolecules, increasing the added value of foods and recovering valuable components from by-products and fermentation media. Many of the methods discussed are now in commercial practice, while others are being vigorously



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回复人:claymore,★★★★★ (C-H活化,kumada,suzuki,stille,negishi.cross-coupling.) 时间:2009-12-29 23:56:12   编辑 3楼
Physical Chemistry(Third Edition)


Physical
Chemistry
Third Edition
Robert G. Mortimer
Professor Emeritus
Rhodes College
Memphis, Tennessee

Cover Design: Eric DeCicco
Cover Image: © iStockphoto
Elsevier Academic Press
30 Corporate Drive, Suite 400, Burlington, MA01803, USA
525 B Street, Suite 1900, San Diego, CA 92101-4495, USA
84 Theobald’s Road, London WC1X 8RR, UK
This book is printed on acid-free paper. ∞
Copyright © 2008, Elsevier Inc. All rights reserved.
No part of this publication may be reproduced or transmitted in any form or by any means,
electronic or mechanical, including photocopy, recording, or any information storage
and retrieval system, without permission in writing from the publisher.
Permissions may be sought directly from Elsevier’s Science & Technology Rights Department in
Oxford, UK: phone: (+44) 1865 843830, fax: (+44) 1865 853333, E-mail: permissions@elsevier.co.uk.
You may also complete your request on-line via the Elsevier homepage (http://elsevier.com), by
selecting “Customer Support” and then “Obtaining Permissions.”
Library of Congress Catalog-in-Publishing Data
Mortimer, Robert G.
Physical chemistry / Robert G. Mortimer. – 3rd ed.
p. cm.
Includes bibliographical references and index.
ISBN 978-0-12-370617-1 (hardcover : alk. paper)
1. Chemistry, Physical and theoretical. I. Title.
QD453.2.M67 2008
541–dc22
2008007675
British Library Cataloguing in Publication Data
A catalogue record for this book is available from the British Library
ISBN-13: 978-0-12-370617-1




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回复人:claymore,★★★★★ (C-H活化,kumada,suzuki,stille,negishi.cross-coupling.) 时间:2009-12-29 23:51:02   编辑 4楼
Genomics in Cancer Drug Discovery and Development
Advances in Cancer Research Volume 96
by: G Hampton, K Sikora, GF Vande Woude, G Klein
Publisher: Academic Press
2006-12
ISBN: 0120066963

The Advances in Cancer Research series provides invaluable information on the exciting and fast-moving field of cancer research. This volume stands as the first ever thematic volume in the series, focusing on the topic of genomics in cancer drug development. The chapters included in this book represent the cutting-edge information in the field and span such topics as Mass Spectrometry: Uncovering the Cancer Proteome for Diagnostics; Biomarker Discovery in Epithelial Ovarian Cancer by Genomic Approaches; The Application of siRNA Technology to Cancer Biology Discovery; Ribozyme Technology for Cancer Gene Target Identification and Validation; Cancer Cell-Based Genomic and Small Molecule Screens; Tumour Antigens as Surrogate Markers and Targets for Therapy and Vaccines; Practices and Pitfalls of Mouse Cancer Models in Drug Discovery; Biomarker Assay Translation from Discovery to Clinical Studies in Cancer Drug Development Quantification of Emerging Protein Biomarkers; Molecular Optical Imaging of Therapeutic Targets of Cancer; Cancer Drug Approval in the United States, Europe and Japan.

Biomarker Discovery in Epithelial Ovarian Cancer
by Genomic Approaches
Samuel C. Mok, Kevin M. Elias, Kwong-Kwok Wong,
Kae Ho, Tomas Bonome, and Michael J. Birrer
I. Introduction 2
II. Genomic Approaches in Biomarker Discovery 5
References 18
Mass Spectrometry: Uncovering the Cancer
Proteome for Diagnostics
Da-Elene van der Merwe, Katerina Oikonomopoulou,
John Marshall, and Eleftherios P. Diamandis
I. Current Cancer Biomarkers 24
II. Early Detection 25
III. The Need for New Diagnostic Strategies 27
IV. Mass Spectrometry 29
V. Mass Spectrometry-Based Diagnostics 32
VI. Current Limitations of Diagnostic Mass Spectrometry 37
VII. Suggestions for Future Progress 42
VIII. Future Direction 43
References 43
Microarrays to Identify New Therapeutic
Strategies for Cancer
Christopher Sears and Scott A. Armstrong
I. Introduction 52
II. Microarray Technologies 52
III. Microarrays in Drug Development 59
IV. Microarrays to Direct the Use of Cancer Therapeutics 60
V. Identification of Therapeutic Targets in Distinct Disease Subtypes 65
VI. Conclusions 70
References 71
The Application of siRNA Technology to
Cancer Biology Discovery
Uta Fuchs and Arndt Borkhardt
I. Introduction 75
II. The Mechanism of RNAi 76
III. Transcriptional Gene Silencing by siRNAs 80
IV. siRNAs Delivery: Strategies and Difficulties 81
V. RNAi as Discovery Tool in Cancer Biology 84
VI. RNAi Screens 87
VII. Limitations of siRNAs as Cancer Therapeutics:
Not Related to Delivery Problems 95
VIII. Summary 96
References 96
Ribozyme Technology for Cancer Gene Target
Identification and Validation
Qi-Xiang Li, Philip Tan, Ning Ke, and Flossie Wong-Staal
I. Brief Biology of Ribozymes 103
II. Ribozymes as Tools for Gene Inactivation 105
III. Ribozymes as Tools in Gene Target Discovery and Validation 109
IV. Ribozyme-Based Genomic Technology in Cancer Gene Target
Discovery and Validation 113
V. Summary 137
References 139
Cancer Cell-Based Genomic and Small Molecule Screens
Jeremy S. Caldwell
I. Introduction 146
II. Drugs, Druggability, and Target Validation 147
III. Post-genomic Discovery of Novel Targets 148
IV. Small Molecule Screens in Oncology 155
V. Conclusions 167
References 168
vi Contents
Tumor Antigens as Surrogate Markers and
Targets for Therapy and Vaccines
Angus Dalgleish and Hardev Pandha
I. Introduction: The Immune System and the Concept of
Tumor Antigens 175
II. How Tumor Antigens Are Recognized 176
III. Cancer Antigens 179
IV. Novel TAA Identification Techniques 180
V. Effective Targeting of TAA in the Clinic 182
VI. TAAs as Therapeutic Targets 184
VII. Cancer Vaccines 184
VIII. Tumor Antigens and Cancer Vaccines 185
IX. Tumor Antigens as Surrogate Markers and Targets for
Therapy and Vaccines 186
X. Summary and Future Directions 187
References 188
Practices and Pitfalls of Mouse Cancer Models in Drug Discovery
Andrew L. Kung
I. Why Are Animal Models Needed? 191
II. Model Types: Tumor Locations 193
III. Tumor Models: Cell Types 198
IV. Study Endpoints 199
V. Animal Modeling in the Post-genomics Age 203
VI. Conclusions 207
References 207
Pharmacodynamic Biomarkers for Molecular Cancer Therapeutics
Debashis Sarker and Paul Workman
I. Introduction 214
II. Types of Biomarkers 216
III. The Pharmacological Audit Trail 218
IV. Methodological Issues 220
V. Rationale for Use of PD Markers to Facilitate
Drug Development 222
VI. The Need for Multidisciplinary and Broad-Based Collaborative Research and Development 229
VII. Biomarker Methodology 230
VIII. Examples of PD Biomarkers for Specific New
Drug Classes 237
IX. Combining Chemotherapy with Molecularly Targeted Agents 252
X. Conclusions and Future Perspective 253
References 255
Biomarker Assay Translation from Discovery to
Clinical Studies in Cancer Drug Development:
Quantification of Emerging Protein Biomarkers
Jean W. Lee, Daniel Figeys, and Julian Vasilescu
I. Introduction 270
II. Biomarkers and Cancer Drug Development 272
III. Biomarker Research Challenges: Technology Translation 275
IV. Biomarker Research Challenges: Cultural and Process Translation 281
V. Clinical Qualification 291
VI. Conclusions and Perspectives 294
References 296
Molecular Optical Imaging of Therapeutic Targets of Cancer
Konstantin Sokolov, Dawn Nida, Michael Descour, Alicia Lacy,
Matthew Levy, Brad Hall, Su Dharmawardhane,
Andrew Ellington, Brian Korgel, and Rebecca Richards-Kortum
I. Introduction 300
II. Role of Molecular-Specific Optical Imaging of Carcinogenesis 302
III. Cancer Biomarkers and Therapeutic Targets 304
IV. Optical Technologies 306
V. Optically Active Contrast Agents 311
VI. Delivery of Contrast Agents In Vivo 322
VII. Molecular-Specific Optical Imaging 324
VIII. Future Directions: ‘‘Smart’’ Contrast Agents 331
IX. Conclusions 335
References 336
Personalized Medicine for Cancer: From Molecular
Signature to Therapeutic Choice
Karol Sikora
I. Summary 345
II. Introduction 346
III. Prevention and Screening 351
IV. Detecting Cancer 353
viii Contents
V. New Treatment Approaches 354
VI. The Development of Personalized Medicine 357
VII. Barriers to Innovation 361
VIII. Patient’s Experience 363
IX. Conclusions 365
References 369
Cancer Drug Approval in the United States,
Europe, and Japan
R. A. V. Milsted
I. USA 371
II. Europe 381
III. Japan 384
IV. Discussion 387
Index 393



回复人:claymore,★★★★★ (C-H活化,kumada,suzuki,stille,negishi.cross-coupling.) 时间:2010-02-01 18:36:38   编辑 5楼
The Mathematics of Physics and Chemistry - Volume Two
By Henry Margenau, George Moseley Murphy



•Publisher: Van Nostrand
•Number Of Pages: 786
•Publication Date: 1964
•ISBN-10 / ASIN: B000L6I8IY
•ISBN-13 / EAN:


The mathematics of physics and chemistry, volume 1
By Henry Margenau

--------------------------------------------------------------------------------
Editorial Reviews
Product Description
Many of the earliest books, particularly those dating back to the 1900s and before, are now extremely scarce and increasingly expensive. We are republishing these classic works in affordable, high quality, modern editions, using the original text and artwork. --This text refers to the Paperback edition.

--------------------------------------------------------------------------------
Product Details
Unknown Binding: 604 pages
Publisher: R. E. Krieger Pub. Co; 2nd edition (1976)
Language: English
ISBN-10: 0882754238
ISBN-13: 978-0882754239
Average Customer Review

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回复人:claymore,★★★★★ (C-H活化,kumada,suzuki,stille,negishi.cross-coupling.) 时间:2009-12-26 13:18:11   编辑 6楼
The Mesoscopic Theory of Polymer Dynamics (Springer Series in Chemical Physics)
by: Vladimir N. Pokrovskii
en | Springer

9048122309 9789048122301

The Mesoscopic Theory of Polymer Dynamics (Springer Series in Chemical Physics)
By Vladimir N. Pokrovskii



•Publisher: Springer
•Number Of Pages: 256
•Publication Date: 2010-01-01
•ISBN-10 / ASIN: 9048122309
•ISBN-13 / EAN: 9789048122301


Product Description:


The theory presented in this book explains in a consistent manner all dynamic effects (diffusion, neutron scattering, viscoelasticity, optical birefringence) observed in very concentrated solutions and melts of linear polymers from a macromolecular point of view. This monograph reconciles different approaches to polymer dynamics and reflects the modern situation in understanding the relaxation behaviour of the polymer systems. The reader is invited to follow the way from dynamics of a separate macromolecule to the constitutive relations for both weakly and strongly entangled linear polymers. The contents can be related to the fields of molecular physics, fluid mechanics, polymer physics and materials science. This text provides material for one or two semester graduate-level course in polymer dynamics or for graduate students with some background in physics and mathematics. The monograph presents topics in a self-contained way that makes it a suitable reference book for professional researchers in the fields of polymer science, polymer engineering, and materials science.



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回复人:我住村外, (永远不够用——知识and人民币。) 时间:2011-03-26 12:36:38   编辑 7楼
资源不错,加1分


回复人:claymore,★★★★★ (C-H活化,kumada,suzuki,stille,negishi.cross-coupling.) 时间:2009-11-06 15:11:59   编辑 8楼
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回复人:claymore,★★★★★ (C-H活化,kumada,suzuki,stille,negishi.cross-coupling.) 时间:2010-02-01 18:39:38   编辑 9楼
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回复人:claymore,★★★★★ (C-H活化,kumada,suzuki,stille,negishi.cross-coupling.) 时间:2009-11-06 15:10:34   编辑 10楼
By
Richard Sundberg, The University of Virginia
Alan Katritzky, University of Florida, Gainesville, USA
O. Meth-Cohn, University of Sunderland, UK
C. Rees, Imperial College of Science and Technology, London, UK

Included in series
Best Synthetic Methods,

Description
Indoles continue to be of great interest to the pharmaceutical industry and at the current time several thousand specific new derivatives are reported annually. Research has been driven by the wide range of indole derivatives which occur in nature and through the biological activity of many indole derivatives, of both natural and synthetic origin.This book provides a systematic guide to the most useful and important reactions in the field for both synthesis and synthetic modification of the indole ring. While including the most recently developed and promising methods, it also updates informationavailable on classical methods to give the reader an up-to-date and comprehensive view of the subject. The methods are illustrated by procedures drawn from the literature and by tables including examples chosen to indicate both the scope of applicabilityand variations in methodology. The organization of the book is based on the retrosynthetic concept of identifying the bond(s) formed in the reaction, which in turn identifies potential starting materials.

Audience
Synthetic chemists in academia and industry.

Contents
Introduction. Category Ia Cyclizations. Category Ib Cyclizations. Category Ic Cyclizations. Category Ii Cyclizations. Category IIab Cyclizations. Category IIac Cyclizations. Indoles by Annelation of Pyrroles. Synthetic Modification of Indoles by Substitution at Nitrogen. Introduction of Substituents at C2. Introduction of Substituents at C3. Modification of 3-Alkyl Substituents by Nucleophilic Substitution. Introduction of the Tryptamine andTryptophan Side-Chains. Introduction of the Substituents on the Carbocyclic Ring. Selective Reduction and Oxidation Reactions. Synthetic Elaboration for Indole Derivatives using Cycloaddition Reactions. Subject Index.



回复人:claymore,★★★★★ (C-H活化,kumada,suzuki,stille,negishi.cross-coupling.) 时间:2009-11-06 15:11:25   编辑 11楼
Copyright © 1996 Elsevier Ltd. All rights reserved

Author(s): R.J. Sundberg
ISBN: 978-0-12-676945-6
Table of Contents



Foreword, Page vii
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Preface, Page viii
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1 - Introduction, Pages 1-6
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2 - Category Ia Cyclizations, Pages 7-26
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3 - Category Ib Cyclizations, Pages 27-33
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4 - Category Ic Cyclizations, Pages 35-44
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5 - Category Ii Cyclization—The Hemetsberger Synthesis, Pages 45-47
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6 - Category IIab Cyclizations, Pages 49-51
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7 - Category IIac Cyclizations, Pages 53-78
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8 - Indoles by Annelation of Pyrroles, Pages 79-87
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9 - Synthetic Modification of Indoles by Substitution at Nitrogen, Pages 89-93
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10 - Introduction of Substituents at C2, Pages 95-103
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11 - Introduction of Substituents at C3, Pages 105-118
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12 - Modification of 3-Alkyl Substituents by Nucleophilic Substitution, Pages 119-124
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13 - Introduction of the Tryptamine and Tryptophan Side-Chains, Pages 125-134
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14 - Introduction of Substituents on the Carbocyclic Ring, Pages 135-144
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15 - Selective Reduction and Oxidation Reactions, Pages 145-158
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16 - Synthetic Elaboration of Indole Derivatives using Cycloaddition Reactions, Pages 159-169
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Index of Compounds and Methods, Pages 171-175
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回复人:claymore,★★★★★ (C-H活化,kumada,suzuki,stille,negishi.cross-coupling.) 时间:2009-11-04 21:41:24   编辑 12楼
【Wiley】【高清DJVU】【Thiazole and its Derivatives】【1979】


回复人:claymore,★★★★★ (C-H活化,kumada,suzuki,stille,negishi.cross-coupling.) 时间:2009-11-04 21:42:21   编辑 13楼
1-3卷


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回复人:claymore,★★★★★ (C-H活化,kumada,suzuki,stille,negishi.cross-coupling.) 时间:2009-12-26 20:42:20   编辑 14楼
Sustainable Industrial Chemistry
by: Fabrizio Cavani, Gabriele Centi, Siglinda Perathoner, Ferruccio Trifirò


Sustainable Industrial Chemistry
By Fabrizio Cavani, Gabriele Centi, Siglinda Perathoner, Ferruccio Trifirò



•Publisher: Wiley-VCH
•Number Of Pages: 621
•Publication Date: 2009-12-14
•ISBN-10 / ASIN: 3527315527
•ISBN-13 / EAN: 9783527315529


Product Description:

There are various books on green chemistry on the market, but without focus on sustainable industrial processes. This resource provides an overview of the new trends and hot topics in process design, describing the challenge of designing industrial chemical processes that are up-to-date, sustainable, and economically feasible. The industrial applications are presented directly by the companies – a veritable “Who’s Who” of the chemical industry – that developed these innovative technologies. It provides an essential reference for chemical engineers, chemists in industry, process engineers, catalytic chemists, materials scientists, and environmental chemists.


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回复人:claymore,★★★★★ (C-H活化,kumada,suzuki,stille,negishi.cross-coupling.) 时间:2009-10-01 09:59:45   编辑 15楼
The Logic of Chemical Synthesis (Paperback)
by E. J. Corey
E. J. Corey (Author)
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(Author), Xue-Min Cheng (Author) "1.1 Multislep chemical Synthesis. . . . . . . . . . . . . . . . . . . .1..." (more)
Key Phrases: retrosynthetic conversion, retrosynthetic simplification, powerfully simplifying transform, Tetrahedron Lett, New York, Academic Press (more...




The Logic of Chemical Synthesis The title of this three-part volume derives from a key theme of the book-the logic underlying the rational analysis of complex synthetic problems. Although the book deals almost exclusively with molecules of biological origin, which are ideal for developing the fundamental ideas of multistep synthetic design because of their architectural complexity and variety, the approach taken is fully applicable to other types of carbon-based structures. Part One outlines the basic concepts of retrosynthetic analysis and the general strategies for generating possible synthetic pathways by logical reduction of molecular complexity. Systematic retrosynthetic analysis and the concurrent use of multiple independent strategies to guide problem solving greatly simplify the task of devising a new synthesis. This way of thinking has been used for more than two decades by one of the authors to teach the analysis of difficult synthetic problems to many hundreds of chemists. A substantial fraction of the intricate syntheses which have appeared in the literature in recent years have been produced by these individuals and their students. Part Two, a collection of multistep syntheses, provides much integrated information on synthetic methods and pathways for the construction of interesting target molecules. These syntheses are the result of synthetic planning which was based on the general principles summarized in Part One. Thus, Part Two serves to supplement Part One with emphasis on the reactions of synthesis and on specific examples of retrosynthetically planned syntheses. Part Three is intended to balance the coverage of Parts One and Two and to serve as a convenient guide to the now enormous literature of multistep synthesis. Information on more than six hundred interesting multistep syntheses of biologically derived molecules is included. It is hoped that the structural range and variety of target molecules presented in Part Three will appeal to many chemists.

From the Back Cover
The Logic of Chemical Synthesis The title of this three-part volume derives from a key theme of the book—the logic underlying the rational analysis of complex synthetic problems. Although the book deals almost exclusively with molecules of biological origin, which are ideal for developing the fundamental ideas of multistep synthetic design because of their architectural complexity and variety, the approach taken is fully applicable to other types of carbon-based structures. Part One outlines the basic concepts of retrosynthetic analysis and the general strategies for generating possible synthetic pathways by logical reduction of molecular complexity. Systematic retrosynthetic analysis and the concurrent use of multiple independent strategies to guide problem solving greatly simplify the task of devising a new synthesis. This way of thinking has been used for more than two decades by one of the authors to teach the analysis of difficult synthetic problems to many hundreds of chemists. A substantial fraction of the intricate syntheses which have appeared in the literature in recent years have been produced by these individuals and their students. Part Two, a collection of multistep syntheses, provides much integrated information on synthetic methods and pathways for the construction of interesting target molecules. These syntheses are the result of synthetic planning which was based on the general principles summarized in Part One. Thus, Part Two serves to supplement Part One with emphasis on the reactions of synthesis and on specific examples of retrosynthetically planned syntheses. Part Three is intended to balance the coverage of Parts One and Two and to serve as a convenient guide to the now enormous literature of multistep synthesis. Information on more than six hundred interesting multistep syntheses of biologically derived molecules is included. It is hoped that the structural range and variety of target molecules presented in Part Three will appeal to many chemists.



Paperback: 436 pages
Publisher: Wiley-Interscience; 1 edition (June 29, 1995)
Language: English
ISBN-10: 0471115940
ISBN-13: 978-0471115946
Product Dimensions: 9.9 x 7.1 x 0.6 inches



回复人:claymore,★★★★★ (C-H活化,kumada,suzuki,stille,negishi.cross-coupling.) 时间:2009-10-01 10:00:14   编辑 16楼
The Logic Of Chemical Synthesis_ E.J.Corey,Wiley


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回复人:claymore,★★★★★ (C-H活化,kumada,suzuki,stille,negishi.cross-coupling.) 时间:2009-10-01 10:03:46   编辑 17楼
Advanced Organic Synthesis


(ISBN: 0125049501 ) Richard S. Monson



The developments in organic synthesis in recent years have been as dramatic as any that have occurred in laboratory sciences. One need only mention a few terms to understand that chemical systems that did not exist twenty years ago have become as much a part of the repertoire of the synthetic organic chemist as borosilicate glassware. The list of such terms would include the Wittig reaction, enamines, carbenes, hydride reductions, the Birch reduction, hydroboration, and so on. Surprisingly, an introduction to the manipulations of these reaction techniques for the undergraduate or graduate student has failed to materialize, and it is often necessary for students interested in organic synthesis to approach modern synthetic reactions in a haphazard manner.

The purpose of this text is to provide a survey, and systematic introduction to, the modern techniques of organic synthesis for the advanced undergraduate student or the beginning graduate student. An attempt has been made to acquaint the student with a variety of laboratory techniques as well as to introduce him to chemical reagents that require deftness and care in handling. Experiments have been drawn from the standard literature of organic synthesis including suitable modifications of several of the reliable and useful preparations that have appeared in Organic Synthesis. Other examples have been drawn from the original literature. Where ever possible, the experiments have been adapted to the locker complement commonly found in the advanced synthesis course employing intermediate scale standard taper glassware. Special equipment for the performance of some of the syntheses would include low-pressure hydrogenation apparatus, ultraviolet lamps and reaction vessels, Dry Ice (cold finger) condensers, vacuum sublimation and distillation apparatus, and spectroscopic and chromatographic instruments. In general, an attempt has been made to employ as substrates materials that are available commercially at reasonable cost, although several of the experiments require precursor materials whose preparation is detailed in the text. Some of the reagents are hazardous to handle, but I believe that, under reasonable supervision, advanced students will be able to perform the experiments with safety.

Introductory discussion of the scope and mechanism of each reaction has been kept to a minimum. Many excellent texts and reviews exist that provide thorough and accurate discussion of the more theoretical aspects of organic synthesis, and the student is referred to these sources and to the original literature frequently. Since it is the purpose of this volume to provide technical procedures, no useful purpose would be served in merely duplicating previously explicated theoretical material.

The number of experiments that can be done satisfactorily in a one-semester course varies widely with the physical situation and the individual skills of the student. Therefore, no attempt is made to suggest a schedule. I recommend, however, that a common core of about five experiments be assigned. The remainder of the preparations can then be chosen by individual students as dictated by their interests as well as by the availability of chemicals and special equipment. The common experiments, representing frequently used and important techniques, might be chosen from Chapter 1, Sections I and IV; Chapter 2, Section I; Chapter 3, Section I; Chapter 4, Section I; Chapter 5, Section I; Chapter 6, Sections III and IV; Chapter 7, Sections II and VI; Chapter 8, Section II; Chapter 9, Sections I and II; Chapter 11, Sections I and III; or Chapter 13, Section II. Since many of the other experiments draw on the products of this suggested list, the possibility of multistep syntheses also presents itself, and several such sequences are outlined in Appendix 1. Also included, in Appendix 2, are the commercial suppliers of the chemicals required when these chemicals are not routinely available.

Finally, a brief introduction to the techniques of synthesis is given in Appendix 3. Students with no synthetic experience beyond the first-year organic chemistry course are advised to skim through this section in order to acquaint themselves with some of the apparatus and terminology used in the description of synthetic procedures.

RICHARD S. MONSON



回复人:claymore,★★★★★ (C-H活化,kumada,suzuki,stille,negishi.cross-coupling.) 时间:2009-10-01 10:04:19   编辑 18楼
Advanced Organic Synthesis, 1971,RICHARD S. MONSON

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回复人:claymore,★★★★★ (C-H活化,kumada,suzuki,stille,negishi.cross-coupling.) 时间:2009-10-01 10:08:16   编辑 19楼
Greene's Protective Groups in Organic Synthesis, 4th Edition
Peter G. M. Wuts, Theodora W. Greene
ISBN: 978-0-471-69754-1
Hardcover
1110 pages
October 2006



The Fourth Edition of Greene's Protective Groups in Organic Synthesis continues to be an indispensable reference for controlling the reactivity of the most common functional groups during a synthetic sequence. This new edition incorporates the significant developments in the field since publication of the third edition in 1998, including...
New protective groups such as the fluorous family and the uniquely removable 2-methoxybenzenesulfonyl group for the protection of amines
New techniques for the formation and cleavage of existing protective groups, with examples to illustrate each new technique
Expanded coverage of the unexpected side reactions that occur with protective groups
New chart covering the selective deprotection of silyl ethers
3,100 new references from the professional literature






Preface to the Fourth Edition.
Preface to the Third Edition.

Preface to the Second Edition.

Preface to the First Edition.

Abbreviations.

1. The Role of Protective Groups in Organic Synthesis.

2. Protection for the Hydroxyl Group, Including 1,2- and 1,3-Diols.

Ethers.

Esters.

Protection for 1,2- and 1,3-Diols.

3. Protection for Phenols and Catechols.

Protection for Phenols.

Ethers.

Silyl Ethers.

Esters.

Carbonates.

Aryl Carbamates.

Phosphinates.

Sulfonates.

Protection for Catechols.

Cyclic Acetals and Ketals.

Cyclic Esters.

Protection for 2-Hydroxybenzenethiols.

4. Protection for the Carbonyl Group.

Acetals and Ketals.

Miscellaneous Derivatives.

Monoprotection of Dicarbonyl Compounds.

5. Protection for the Carboxyl Group.

Esters.

Amides and Hydrazides.

Protection of Boronic Acids.

Protection of Sulfonic Acids.

6. Protection for the Thiol Group.

Thioethers.

Thioesters.

Miscellaneous Derivatives.

7. Protection for the Amino Group.

Carbamates.

Amides.

Special —NH Protective Groups.

Protection for Imidazoles, Pyrroles, Indoles, and other Aromatic Heterocycles.

Protection for the Amide —NH.

Protection for the Sulfonamide —NH.

8. Protection for the Alkyne —CH.

9. Protection for the Phosphate Group.

Some General Methods for Phosphate Ester Formation.

Removal of Protective Groups from Phosphorus.

Alkyl Phosphates.

Phosphates Cleaved by Cyclodeesterifi cation.

Benzyl Phosphates.

Phenyl Phosphates.

Photochemically Cleaved Phosphate Protective Groups.

Amidates.

Miscellaneous Derivatives.

10. Reactivities, Reagents, and Reactivity Charts.

Reactivities.

Reagents.

Reactivity Charts.

1 Protection for the Hydroxyl Group: Ethers.

2 Protection for the Hydroxyl Group: Esters.

3 Protection for 1,2- and 1,3-Diols.

4 Protection for Phenols and Catechols.

5 Protection for the Carbonyl Group.

6 Protection for the Carboxyl Group.

7 Protection for the Thiol Group.

8 Protection for the Amino Group: Carbamates.

9 Protection for the Amino Group: Amides.

10 Protection for the Amino Group: Special —NH Protective Groups.

11 Selective Deprotection of Silyl Ethers.

Index.



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Greenes Protective Groups in Organic Synthesis


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Organic Chemistry
includes Study Guide/Solutions Manual Fourth Edition G. Marc Loudon and Joseph G. Stowell




ISBN13: 9780195159127
ISBN10: 0195159128
Hardback,



Description
This package includes G. Marc Loudon's textbook Organic Chemistry, Fourth Edition (0-19-511999-1) and its accompanying Study Guide/Solutions Manual (0-19-512000-0) at a discounted price. Product Details
7-1/2 x 9-1/4;
ISBN13: 978-0-19-515912-7
ISBN10: 0-19-515912-8
About the Author(s)








Organic Chemistry,4th_ 2006,Bruice


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Metals and Ligand Reactivity: An Introduction to the Organic Chemistry of Metal Complexes



By addebook • Nov 22nd, 2008 • Category: Materials


Publisher: Wiley-VCH
Number Of Pages: 308
Publication Date: 1996-01-18
ISBN-10 / ASIN: 3527292780
ISBN-13 / EAN: 9783527292783
Binding: Hardcover







This book is a highly readable introduction to the reactions of coordinated ligands, which have become a useful tool in organic synthesis. Bridging the gap between the traditional fields, this text presents the basic concepts of ligand reactivity as well as synthetic applications of these reactions.



Topics covered include



* Principles of metal-ligand interaction * Reactions of coordinated ligands with nucleophiles and electrophiles * Oxidation and reduction of coordinated ligands * Cyclic and encapsulating ligands, template effect and supramolecular chemistry



Metals and Ligard Reactivity


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Modern Organic Synthesis in the Laboratory (Paperback)
by Jie Jack Li
Jie Jack Li (Author)
› Visit Amazon's Jie Jack Li Page
Find all the books, read about the author, and more.
See search results for this author
Are you an author? Learn about Author Central
(Author), Chris Limberakis (Author), Derek A. Pflum (Author)



Modern Organic Synthesis in the Laboratory


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Protecting Group Strategies in Organic Synthesis, ANGEW



Angewandte Chemie International Edition in English
Volume 35 Issue 18, Pages 2056 - 2083
Published Online: 22 Dec 2003

Copyright © 1997 Wiley-VCH Verlag GmbH, Weinheim


Review
Protecting Group Strategies in Organic Synthesis
Dipl.-Chem. Michael Schelhaas, Prof. Dr. Herbert Waldmann *
Institut für Organische Chemie der Universität Karlsruhe Richard-Willstätter-Allee 2, D-76128 Karlsruhe (Germany) Fax: Int. code +(721)608-4825 email: waldmann@ochhades.chemie.uni-karlsruhe.de


*Correspondence to Herbert Waldmann, Institut für Organische Chemie der Universität Karlsruhe Richard-Willstätter-Allee 2, D-76128 Karlsruhe (Germany) Fax: Int. code +(721)608-4825 email: waldmann@ochhades.chemie.uni-karlsruhe.de

Dedicated to Professor Leopold Horner on the occasion of his 85th birthday

Keywords
protecting groups • retrosynthetic analyses • synthetic methods • total synthesesProtecting groups • Retro reactions • Synthetic methods • Total synthesis


Abstract
The choice of protecting groups is one of the decisive factors in the successful realization of a complex, demanding synthetic project. The protecting groups used influence the length and efficiency of the synthesis and are often responsible for its success or failure. A wide range of blocking groups are currently available for the different functional groups; however, an overall strategy combining these different masking techniques in an advantageous and reliable manner has never been proposed or at best only for individual cases. This review attempts to make a contribution to filling this gap. First a very short overview of the most commonly used protecting groups will be given, in which they are classified according to their lability and not according to the functional group they protect. This classification clarifies coherent concepts for the development of blocking strategies. On the basis of this brief summary reliable strategies will then be illustrated and developed with selected examples from the recent literature by which protecting groups may be combined successfully and advantageously in synthetic projects of differing degrees of complexity and difficulty.



--------------------------------------------------------------------------------
Received: 15 December 1995; Revised: 11 March 1996
Digital Object Identifier (DOI)

10.1002/anie.199620561 About DOI





Protecting Group Strategies in Organic Synthesis, ANGEW




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Synthesis of Heterocycles via Cycloadditions I
Series: Topics in Heterocyclic Chemistry , Vol. 12
Volume package Synthesis of Heterocycles via Cycloadditions

Hassner, Alfred (Ed.)

2008, XII, 230 p. 283 illus., Hardcover

ISBN: 978-3-540-78368-8




Synthesis of Heterocycles via Cycloadditions

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Preface
Heterocyclic molecules play a significant role in life processes and have played
a major role in industrial developments of the last century, for instance in the
field of dyes, pharmaceuticals, pesticides, polymers etc. They comprise not
only some of themost interesting and biologically important natural products
like alkaloids, carbohydrates, nucleic acids, and antibiotics but include many
practical drugs and a large segment of known synthetic organic compounds.
Hence scientists have devoted a great amount of effort to find optimal synthetic
approaches to a variety of heterocyclic compounds.
Among the most successful and selective synthetic processes are cycloaddition
reactions, since they involve simultaneous or sequential formation of two
or more bonds oftenwith a high degree of stereoselectivity and regioselectivity.
For instance, 1,3 dipolar cycloadditions are electronically equivalent to Diels–
Alder reactions and are among the most common 5-membered ring-forming
systems. In addition they usually proceed with a high degree of stereo- and
regio-control. It is therefore, not surprising that synthesis of many important
classes of heterocycles, including those of useful biologically active molecules,
have utilized cycloaddition steps in their formation. Furthermore, many heterocycles
serve as intermediates in the synthesis of polyfunctional molecules.
In this volume we present five selected contributions by well-known authors,
each an authority in his field. The first chapter deals with construction
of isoxazolines (dihydroisoxazoles) via 1,3-dipolar cycloadditions of nitronates
or of nitrile oxides generated from nitroalkanes. This includes inter- as well
as intramolecular processes. Many of these heterocycles possess important
synthetic and biological properties and are shown to lead to stereo- and regioselective
introduction ofmultifunctionalmolecules such as amino alcohols,
β-amino acids, aldols, nitriles, and others.
The second chapter is devoted to cycloadditions of azides, which comprise
a highly versatile functional group. The chapter discusses both catalyzed and
non-catalyzed (thermal) cycloadditions of azides to multiple bonds leading
to many interesting classes of N-heterocycles. Both inter- and intramolecular
azide cycloaddition reactions are featured. Furthermore, bioconjugation involving
azides and their use in tagging of proteins, DNA as well as of living
systems are highlighted.
X Preface
Enantioselective 1,3-dipolar cycloadditions employing azomethine ylides
and asymmetric catalysis are discussed in the next chapter. The formation of
chiral non-racemic pyrrolidine derivatives via dipolar cycloadditions presents
an important challenge that has been successfully overcome. The role of catalysis
involving different metals is also highlighted.
Chapter 4 concerns the cycloaddition of carbonyl ylides generated from
diazo carbonyl compounds and rhodiumor copper catalysts. In this framework
chemoselective and enantioselective transformations leading to the formation
of various heterocycles such as tetrahydrofurans, oxazolidines, mesoionic and
bicyclic compounds, alkaloids, and other natural products are described.
The final chapter deals with phosphorus ylides, in particular of phosphacumulenes,
and their utilization in the synthesis of a number of heterocyclic ring
systems including butenolides, tetramates, and macrolides. I want to thank all
authors for their excellent presentations and their splendid cooperation.
This volume is dedicated with love to my children Lilly and Lawrence and
their families.
Ramat Gan, February 2008 Alfred Hassner



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Carbohydrates: Synthesis, Mechanisms, and Stereoelectronic Effects (Hardcover)
by Momcilo Miljkovic (Author)





Product Details
Hardcover: 543 pages
Publisher: Springer; 1 edition (Sep 22 2009)
Language: English
ISBN-10: 0387922644
ISBN-13: 978-0387922645



Carbohydrates Synthesis, Mechanisms, and Stereoelectronic Effects

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Modern Rhodium-Catalyzed Organic Reactions
P. Andrew Evans (Editor), Jiro Tsuji (Foreword by)
ISBN: 978-3-527-30683-1
Hardcover
496 pages
April 2005




Rhodium has proven to be an extremely useful metal due to its ability to catalyze an array of synthetic transformations, with quite often-unique selectivity. Hydrogenation, C-H activation, allylic substitution, and numerous other reactions are catalyzed by this metal, which presumably accounts for the dramatic increase in the number of articles that have recently emerged on the topic.
P. Andrew Evans, the editor of this much-needed book, has assembled an internationally renowned team to present the first comprehensive coverage of this important area. The book features contributions from leaders in the field of rhodium-catalyzed reactions, and thereby provides a detailed account of the most current developments, including:

Rhodium-Catalyzed Asymmetric Hydrogenation (Zhang)
Rhodium-Catalyzed Hydroborations and Related Reactions (Brown)
Rhodium-Catalyzed Asymmetric Addition of Organometallic Reagents to Electron Deficient Olefins (Hayashi)
Recent Advances in Rhodium(I)-Catalyzed Asymmetric Olefin Isomerization and Hydroacylation Reactions (Fu)
Stereoselective Rhodium(I)-Catalyzed Hydroformylation and Silylformylation Reactions and Their Application to Organic Synthesis (Leighton)
Carbon-Carbon Bond-Forming Reactions Starting from Rh-H or Rh-Si Species (Matsuda)
Rhodium(I)-Catalyzed Cycloisomerization and Cyclotrimerization Reactions (Ojima)
The Rhodium(I)-Catalyzed Alder-ene Reaction (Brummond)
Rhodium-Catalyzed Nucleophilic Ring Cleaving Reactions of Allylic Ethers and Amines (Fagnou)
Rhodium(I)-Catalyzed Allylic Substitution Reactions and their Applications to Target Directed Synthesis (Evans)
Rhodium(I)-Catalyzed [2+2+1] and [4+1] Carbocyclization Reactions (Jeong)
Rhodium(I)-Catalyzed [4+2] and [4+2+2] Carbocyclizations (Robinson)
Rhodium(I)-Catalyzed [5+2], [6+2], and [5+2+1] Cycloadditions: New Reactions for Organic Synthesis (Wender)
Rhodium(II)-Stabilized Carbenoids Containing both Donor and Acceptor Substituents (Davies)
Chiral Dirhodium(II)Carboxamidates for Asymmetric Cyclopropanation and Carbon-Hydrogen Insertion Reactions (Doyle)
Cyclopentane Construction by Rhodium(II)-Mediated Intramolecular C-H Insertion (Taber)
Rhodium(II)-Catalyzed Oxidative Amination (DuBois)
Rearrangement Processes of Oxonium and Ammonium Ylides Formed by Rhodium(II)-Catalyzed Carbene-Transfer (West)
Rhodium(II)-Catalyzed 1,3-Dipolar Cycloaddition Reactions (Austin)





Foreword.
Preface.

List of Contributors.

1 Rhodium-Catalyzed Asymmetric Hydrogenation (Yongxiang Chi, Wenjun Tang, and Xumu Zhang).

1.1 Introduction.

1.2 Chiral Phosphorous Ligands.

1.3 Applications of Chiral Phosphorous Ligands in Rhodium-Catalyzed Asymmetric Hydrogenation.

1.4 Conclusion.

1.5 References.

2 Rhodium-Catalyzed Hydroborations and Related Reactions (John M. Brown).

2.1 Introduction.

2.2 General Advances in Catalytic Hydroboration.

2.3 Advances in Asymmetric Hydroboration.

2.4 Catalytic Diboration of Alkenes.

2.5 Summary and Conclusions.

2.6 References.

3 Rhodium(I)-Catalyzed Asymmetric Addition of Organometallic Reagents to Electron-Deficient Olefins (Kazuhiro Yoshida and Tamio Hayashi).

3.1 Introduction.

3.2 Addition of Organoboron Reagents to α,β-Unsaturated Ketones.

3.3 Mechanism.

3.4 Addition of Organoboron Reagents to Other Electron-Deficient Olefins.

3.5 Addition of Organotin and -silicon Reagents.

3.6 New Aspects of Addition of Organoboron and -titanium Reagents.

3.7 Outlook.

3.8 References.

4 Recent Advances in Rhodium(I)-Catalyzed Asymmetric Olefin Isomerization and Hydroacylation Reactions (Gregory C. Fu).

4.1 Rhodium(I)-Catalyzed Asymmetric Isomerization of Olefins.

4.2 Rhodium(I)-Catalyzed Asymmetric Hydroacylation of Olefins and Alkynes with Aldehydes.

4.3 References.

5 Stereoselective Rhodium(I)-Catalyzed Hydroformylation and Silylformylation Reactions and their Application to Organic Synthesis (James L. Leighton).

5.1 Introduction.

5.2 Hydroformylation.

5.3 Silylformylation.

5.4 Conclusion.

5.5 References.

6 Carbon–Carbon Bond–Forming Reactions Starting from Rh–H or Rh–Si Species (Isamu Matsuda).

6.1 Introduction.

6.2 Background.

6.3 Design of Reactions Starting from Insertion into a Rh–H Bond.

6.4 Design of Reactions Starting from Insertion into a Rh–Si Bond.

6.5 Conclusion.

6.6 References.

7 Rhodium(I)-Catalyzed Cycloisomerization and Cyclotrimerization Reactions (Masaki Fujiwara and Iwao Ojima).

7.1 Introduction.

7.2 Carbocyclization.

7.3 Cascade Carbocyclization.

7.4 Carbonylative Carbocyclization.

7.5 Conclusion.

7.6 References.

8 The Rhodium(I)-Catalyzed Alder-Ene Reaction (Kay M. Brummond and Jamie M. McCabe).

8.1 Introduction.

8.2 Diene Alder-Ene Reactions.

8.3 Enyne Alder-Ene Reactions.

8.4 Allenyne Alder-Ene Reactions.

8.5 Kinetic Resolution.

8.6 Other Rhodium-Catalyzed Ene-Type Reactions.

8.7 Conclusion.

8.8 References.

9 Rhodium-Catalyzed Nucleophilic Ring Cleaving Reactions of Allylic Ethers and Amines (Keith Fagnou).

9.1 Introduction.

9.2 Seminal Work.

9.3 Asymmetric Reactions with Oxabicyclic Alkenes.

9.4 Azabicyclic Alkenes.

9.5 Properties of the PPF-P<sup>t</sup>Bu<sub>2</sub> Ligand.

9.6 Mechanistic Working Model.

9.7 Vinyl Epoxides.

9.8 Conclusion.

9.9 References.

10 Rhodium(I)-Catalyzed Allylic Substitution Reactions and their Applications to Target Directed Synthesis (David K. Leahy and P. Andrew Evans).

10.1 Introduction.

10.2 Regioselective Rhodium-Catalyzed Allylic Alkylation.

10.3 Enantiospecific Rhodium-Catalyzed Allylic Alkylation.

10.4 Enantioselective Rhodium-Catalyzed Allylic Alkylations.

10.5 Conclusion.

10.6 References.

11 Rhodium(I)-Catalyzed [2+2+1] and [4+1] Carbocyclization Reactions (Nakcheol Jeong).

11.1 General Introduction to Rhodium-Mediated Carbocyclizations.

11.2 [2+2+1] Carbocyclization.

11.3 [4+1] Carbocyclization.

11.4 Conclusion.

11.5 References.

12 Rhodium(I)-Catalyzed [4+2] and [4+2+2] Carbocyclizations (John E. Robinson).

12.1 Introduction.

12.2 Rhodium(I)-Catalyzed [4+2] Carbocyclization Reactions.

12.3 Rhodium(I)-Catalyzed [4+2+2] Carbocyclization Reactions.

12.4 References.

13 Rhodium(I)-Catalyzed [5+2], [6+2], and [5+2+1] Cycloadditions: New Reactions for Organic Synthesis (Paul A. Wender, Gabriel G. Gamber, and Travis J. Williams).

13.1 Introduction.

13.2 Cycloaddition Approaches to Seven-Membered Rings.

13.3 Design of a Transition Metal-Catalyzed [5+2] Cycloaddition of Vinylcyclopropanes and &Pi;-Systems.

13.4 Intramolecular [5+2] Cycloadditions of VCPs.

13.5 Intermolecular [5+2] Cycloadditions of VCPs and Alkynes.

13.6 Cycloaddition Approaches for Eight-Membered Ring Synthesis.

13.7 Design and Development of [6+2] Cycloadditions of Vinylcyclobutanones.

13.8 Design and Development of Multi-component [5+2+1] Cycloadditions of VCPs, Alkynes, and CO.

13.9 Conclusion.

13.10 References.

14 Rhodium(II)-Stabilized Carbenoids Containing Both Donor and Acceptor Substituents (Huw M.L. Davies and Abbas M. Walji).

14.1 Introduction.

14.2 Cyclopropanation.

14.3 [3+4] Cycloaddition of Vinyl Carbenoids.

14.4 [3+2] Cycloaddition of Vinyl Carbenoids.

14.5 Ylide Transformations.

14.6 Si–H Insertion.

14.7 C–H Activation by Carbenoid-Induced C–H Insertion.

14.8 References.

15 Chiral Dirhodium(II) Carboxamidates for Asymmetric Cyclopropanation and Carbon–Hydrogen Insertion Reactions (Michael P. Doyle).

15.1 Introduction.

15.2 Catalytic Asymmetric Cyclopropanation and Cyclopropenation.

15.3 Catalytic Asymmetric Carbon–Hydrogen Insertion.

15.4 Summary.

15.5 References.

16 Cyclopentane Construction by Rhodium(II)-Mediated Intramolecular C–H Insertion (Douglass F. Taber and Pramod V. Joshi).

16.1 Introduction.

16.2 Background: Cyclization versus Elimination.

16.3 Beginnings of a Computational Approach.

16.4 Comparing and Contrasting Rhodium Catalysts: Four Dimensions of Reactivity.

16.5 Design of an Enantioselective Catalyst.

16.6 Conclusion.

16.7 References.

17 Rhodium(II)-Catalyzed Oxidative Amination (Christine G. Espino and Justin Du Bois).

17.1 Introduction.

17.2 Background.

17.3 Intermolecular C–H Amination with Rhodium(II) Catalysts.

17.4 Intermolecular C–H Amination with Other Metals.

17.5 Intramolecular C–H Amination with Rhodium(II) Catalysts.

17.6 Rhodium(II)-Catalyzed Olefin Aziridination.

17.7 Enantioselective C–H Insertion with Sulfamate Esters.

17.8 Mechanistic Investigations.

17.9 Summary and Outlook for Rhodium(II)-Catalyzed Nitrene Transfer.

17.10 Rhodium(II)-Catalyzed Olefin Diamination.

17.11 Applications of C–H Amination in Synthesis.

17.12 Conclusion.

17.13 References.

18 Rearrangement Processes of Oxonium and Ammonium Ylides Formed by Rhodium(II)-Catalyzed Carbene Transfer (Frederick G. West).

18.1 Introduction.

18.2 Oxonium Ylides.

18.3 Ammonium Ylides.

18.4 Conclusion.

18.5 References.

19 Rhodium(II)-Catalyzed 1,3-Dipolar Cycloaddition Reactions (Ruben M. Savizky and David J. Austin)

19.1 Rhodium(II) in 1,3-Dipole Formation.

19.2 Chemical Aspects of Rhodium-Mediated 1,3-Dipolar Cycloaddition.

19.3 Applications of Rhodium(II)-Mediated 1,3-Dipolar Cycloaddition.

19.4 Conclusion.

19.5 References.

Subject Index.





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X-Ray Analysis and the Structure of Organic Molecules
By Jack D. Dunitz


Publisher: Wiley-VCH
Number Of Pages: 514
Publication Date: 1996-12-16
ISBN-10 / ASIN: 3906390144
ISBN-13 / EAN: 9783906390147
Binding: Hardcover




Jack D. Dunitz X-Ray Analysis and the Structure of Organic Molecules From the Reviews of the First Edition ‘The book may be recommended most heartily to anyone who would like to know how molecular structures are determined and what can be deduced from them apart from their topology. The author is evidently a great admirer of the method and its results. The reviewer would agree that ‘cooking’ is not the only way to bring chemically relevant knowledge to light.’ Angew. Chem., Int. Ed. ‘All the information in this text is of considerable value especially to those engaged in, or about to embark upon, X-ray crystal structure analysis but even more so, perhaps, to the non-specialist who may now proceed profitably and discriminately to read the explosively growing crystallographic literature. The author has certainly succeeded in taking us not only on a guided tour, but at the same time has provided rather more of the kind of detail one expects in the best guidebooks.’ Int. Rev. Phys. Chem. ‘All crystallographers, whatever their special structural interests, should get a copy and keep it by them, and many research supervisors will be very happy to entrust their research students to such a sound and stimulating guide.’ Chem. in Britain







X-Ray Analysis and the Structure of Organic Molecules, 2nd Ed.pdf











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Ionic Liquids in Synthesis
Published Online: 6 Feb 2003

Editor(s): Dr. Peter Wasserscheid, Dr. Thomas Welton

Print ISBN: 3527305157 Online ISBN: 3527600701

Copyright &copy; 2002 Wiley-VCH Verlag GmbH & Co. KGaA









Front Matter and Index (p i-xvi)
Summary | Full Text: PDF (Size: 170K)


Chapter 1:
Introduction (p 1-6)
Prof. John S. Wilkes
Summary | Full Text: PDF (Size: 101K)


Chapter 2:
Synthesis and Purification of Ionic Liquids (p 7-40)
Prof. James H. Davis Jr., Dr. Charles M. Gordon, Dr. Claus Hilgers, Dr. Peter Wasserscheid
Summary | Full Text: PDF (Size: 318K)


Chapter 3:
Physicochemical Properties of Ionic Liquids (p 41-126)
Jennifer L. Anthony, Prof. Dr. Joan F. Brennecke, Dr. John D. Holbrey, Edward J. Maginn, Rob A. Mantz, Prof. Dr. Robin D. Rogers, Dr. Paul C. Trulove, Ann E. Visser, Dr. Tom Welton
Summary | Full Text: PDF (Size: 609K)


Chapter 4:
Molecular Structure and Dynamics (p 127-173)
Prof. W. Robert Carper, Dr. Andreas D鰈le, Christof G. Hanke, Dr. Chris Hardacre, Axel Leuchter, Ruth M. Lynden-Bell, Zhizhong Meng, G黱ter Palmer, Prof. Dr. Joachim Richter
Summary | Full Text: PDF (Size: 1178K)


Chapter 5:
Organic Synthesis (p 174-288)
Dr. Martyn Earle, Alain Foresti鑢, H閘鑞e Olivier-Bourbigou, Dr. Peter Wasserscheid
Summary | Full Text: PDF (Size: 928K)


Chapter 6:
Inorganic Synthesis (p 289-318)
Dr. Frank Endres, Dr. Tom Welton
Summary | Full Text: PDF (Size: 498K)


Chapter 7:
Polymer Synthesis in Ionic Liquids (p 319-335)
Adrian J. Carmichael, Prof. Dr. David M. Haddleton
Summary | Full Text: PDF (Size: 141K)


Chapter 8:
Biocatalytic Reactions in Ionic Liquids (p 336-347)
Prof. Dr. Udo Kragl, Marrit Eckstein, Nicole Kaftzik
Summary | Full Text: PDF (Size: 101K)


Chapter 9:
Outlook (p 348-355)
Dr. Peter Wasserscheid, Dr. Tom Welton
Summary | Full Text: PDF (Size: 113K)



回复人:claymore,★★★★★ (C-H活化,kumada,suzuki,stille,negishi.cross-coupling.) 时间:2009-10-03 07:25:36   编辑 30楼
Ionic Liquids in Synthesis.rar




http://www.brsbox.com/filebox/down/fc/e592e94d18b5fe6fa3ebb500e74f6bfa





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